Zend Studio is a convenient environment to code in PHP, even though it is not currently possible to use it for integrated debugging of PHP-GTK code: its php completion and file management, and phpdoc integration make it very useful for the PHP-GTK environment too. However some settings are necessary to ease its use, due to the specific extensions typically used by PHP-GTK programs: phpw files for applications, and glade / gladep for Glade files storing UIs.

Zend Studio is a convenient environment to code in PHP, which is why many Drupal developers are using it. But some settings are necessary to ease its use, due to the specific extensions Drupal uses.